What measure is best for prioritizing IT projects based on overall investment performance?

The most effective measure for prioritizing IT projects based on overall investment performance is the analysis of investment portfolios. This approach allows organizations to evaluate the potential returns of various IT projects in relation to the investments required for each. By assessing the performance of these projects as part of a larger investment portfolio, decision-makers can identify which initiatives will yield the best financial outcomes, optimize resource allocation, and ultimately enhance the organization's return on investment (ROI).

Analyzing investment portfolios involves consideration of factors such as risk, profitability, alignment with strategic goals, and market trends, enabling a comprehensive view of how each project contributes to the organization's financial performance. This method helps prioritize projects that not only meet business objectives but also demonstrate the best potential for generating value.

In contrast, the other options, while important for governance and compliance, do not directly measure investment performance in the same way. Risk self-assessment completion and performing risk assessments focus on identifying and managing potential risks but do not provide a clear picture of financial returns. Conducting IS audits can offer insights into the effectiveness and compliance of IT projects but is not primarily concerned with prioritizing projects based on their investment performance. Thus, analyzing investment portfolios stands out as the best measure for this specific purpose.